Found 7 matching trials
To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers
PHASE1Study to assess the effect of Selumetinib \[AZD6244; ARRY-142886\] \[Hyd-Su...
To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers
PHASE1Study to assess the effect of Rifampicin on the pharmacokinetics of Selumet...
Dual REctcal Angiogenesis or MEK Inhibition radioTHERAPY Trial
PHASE1To determine the maximum tolerated dose (MTD) of AZD6244 or AZD2171 when co...
Location
The Christie NHS Foundation Trust
A Study to Assess the Relative Bioavailability of Process Variants of Selumetinib in Healthy Male Volunteers
PHASE1A Study to assess, against a reference selumetinib capsule, if the drug lev...
Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C] Selumetinib in Volunteers
PHASE1To evaluate the absorption, distribution, metabolism and excretion (ADME) o...
A Study to Assess the Absolute Bioavailability of Oral Selumetinib in Healthy Male Volunteers.
PHASE1To assess the absolute bioavailability of oral selumetinib in healthy male ...
To Assess the Effect of Food on the Pharmacokinetics of Selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in Healthy Male Volunteers
PHASE1Study to assess the effect of food on the Pharmacokinetics of Selumetinib (...